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Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the ß-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction.
Wang, Zhen; Zhang, Min; Quereda, Victor; Frydman, Sylvia M; Ming, Qianqian; Luca, Vincent C; Duckett, Derek R; Ji, Haitao.
Affiliation
  • Wang Z; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9497, United States.
  • Zhang M; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9497, United States.
  • Quereda V; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9497, United States.
  • Frydman SM; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9497, United States.
  • Ming Q; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9497, United States.
  • Luca VC; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9497, United States.
  • Duckett DR; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9497, United States.
  • Ji H; Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612-9497, United States.
J Med Chem ; 64(16): 12109-12131, 2021 08 26.
Article in En | MEDLINE | ID: mdl-34382808
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Full text: 1 Database: MEDLINE Main subject: Piperidines / Protein Binding / Transcription Factors / Beta Catenin / Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Year: 2021 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Piperidines / Protein Binding / Transcription Factors / Beta Catenin / Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Year: 2021 Type: Article