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Ablation of PDE4B protects from Pseudomonas aeruginosa-induced acute lung injury in mice by ameliorating the cytostorm and associated hypothermia.
Abou Saleh, Lina; Boyd, Abigail; Aragon, Ileana V; Koloteva, Anna; Spadafora, Domenico; Mneimneh, Wadad; Barrington, Robert A; Richter, Wito.
Affiliation
  • Abou Saleh L; Department of Biochemistry & Molecular Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Boyd A; Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Aragon IV; Department of Biochemistry & Molecular Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Koloteva A; Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Spadafora D; Department of Biochemistry & Molecular Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Mneimneh W; Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Barrington RA; Department of Biochemistry & Molecular Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Richter W; Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.
FASEB J ; 35(9): e21797, 2021 09.
Article in En | MEDLINE | ID: mdl-34383981
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Full text: 1 Database: MEDLINE Main subject: Pseudomonas aeruginosa / Pseudomonas Infections / Cyclic Nucleotide Phosphodiesterases, Type 4 / Acute Lung Injury / Hypothermia Type of study: Risk_factors_studies Limits: Animals Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Pseudomonas aeruginosa / Pseudomonas Infections / Cyclic Nucleotide Phosphodiesterases, Type 4 / Acute Lung Injury / Hypothermia Type of study: Risk_factors_studies Limits: Animals Language: En Year: 2021 Type: Article