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IRF4 L116R mutation promotes proliferation of chronic lymphocytic leukemia B cells inducing MYC.
Benatti, Stefania; Atene, Claudio Giacinto; Fiorcari, Stefania; Mesini, Nicolò; Martinelli, Silvia; Zucchini, Patrizia; Bacchelli, Francesca; Maccaferri, Monica; Debbia, Giulia; Potenza, Leonardo; Rossi, Davide; Vallisa, Daniele; Trentin, Livio; Gaidano, Gianluca; Luppi, Mario; Marasca, Roberto; Maffei, Rossana.
Affiliation
  • Benatti S; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Atene CG; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Fiorcari S; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Mesini N; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Martinelli S; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Zucchini P; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Bacchelli F; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Maccaferri M; Department of Oncology and Hematology, Hematology Division, Azienda Ospedaliero-Universitaria of Modena-Policlinico, Modena, Italy.
  • Debbia G; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Potenza L; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Rossi D; Hematology, Oncology Institute of Southern Switzerland and Institute of Oncology Research, Bellinzona, Switzerland.
  • Vallisa D; Division of Hematology, Guglielmo da Saliceto Hospital, Piacenza, Italy.
  • Trentin L; Hematology and Clinical Immunology, Department of Medicine, University of Padua, Padua, Italy.
  • Gaidano G; Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy.
  • Luppi M; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Marasca R; Division of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Maffei R; Department of Oncology and Hematology, Hematology Division, Azienda Ospedaliero-Universitaria of Modena-Policlinico, Modena, Italy.
Hematol Oncol ; 39(5): 707-711, 2021 Dec.
Article in En | MEDLINE | ID: mdl-34431535
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Full text: 1 Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Biomarkers, Tumor / Proto-Oncogene Proteins c-myc / Cell Proliferation / Interferon Regulatory Factors / Mutation Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Humans / Male Language: En Year: 2021 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Biomarkers, Tumor / Proto-Oncogene Proteins c-myc / Cell Proliferation / Interferon Regulatory Factors / Mutation Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Humans / Male Language: En Year: 2021 Type: Article