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Inhibition of the NLRP3/IL-1ß axis protects against sepsis-induced cardiomyopathy.
Busch, Katharina; Kny, Melanie; Huang, Nora; Klassert, Tilman E; Stock, Magdalena; Hahn, Alexander; Graeger, Sebastian; Todiras, Mihail; Schmidt, Sibylle; Chamling, Bishwas; Willenbrock, Michael; Groß, Stefan; Biedenweg, Doreen; Heuser, Arnd; Scheidereit, Claus; Butter, Christian; Felix, Stephan B; Otto, Oliver; Luft, Friedrich C; Slevogt, Hortense; Fielitz, Jens.
Affiliation
  • Busch K; Experimental and Clinical Research Center (ECRC), Charité-Universitätsmedizin Berlin, Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Kny M; Experimental and Clinical Research Center (ECRC), Charité-Universitätsmedizin Berlin, Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Huang N; Experimental and Clinical Research Center (ECRC), Charité-Universitätsmedizin Berlin, Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Klassert TE; Department of Cardiology, Heart Center Brandenburg and Medical School Brandenburg (MHB), Bernau, Germany.
  • Stock M; ZIK Septomics, Host Septomics, Jena, Germany.
  • Hahn A; Jena University Hospital, Integrated Research and Treatment Center - Center for Sepsis Control and Care (CSCC), Jena, Germany.
  • Graeger S; ZIK Septomics, Host Septomics, Jena, Germany.
  • Todiras M; Jena University Hospital, Integrated Research and Treatment Center - Center for Sepsis Control and Care (CSCC), Jena, Germany.
  • Schmidt S; Experimental and Clinical Research Center (ECRC), Charité-Universitätsmedizin Berlin, Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Chamling B; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
  • Willenbrock M; Laboratory of Molecular Biology of Peptide Hormones, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  • Groß S; Nicolae Testemitanu State University of Medicine and Pharmacy, Chișinau, Moldova.
  • Biedenweg D; Experimental and Clinical Research Center (ECRC), Charité-Universitätsmedizin Berlin, Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Heuser A; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
  • Scheidereit C; Department of Internal Medicine B, Molecular Cardiology, University Medicine Greifswald, Greifswald, Germany.
  • Butter C; Signal Transduction in Development and Cancer, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  • Felix SB; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
  • Otto O; Department of Internal Medicine B, Molecular Cardiology, University Medicine Greifswald, Greifswald, Germany.
  • Luft FC; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
  • Slevogt H; Centre for Innovation Competence - Humoral Immune Response in Cardiovascular Diseases, University of Greifswald, Greifswald, Germany.
  • Fielitz J; Animal Phenotyping Facility, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
J Cachexia Sarcopenia Muscle ; 12(6): 1653-1668, 2021 12.
Article in En | MEDLINE | ID: mdl-34472725
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Full text: 1 Database: MEDLINE Main subject: Sepsis / Cardiomyopathies Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Year: 2021 Type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Sepsis / Cardiomyopathies Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Year: 2021 Type: Article