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Maternal but not fetoplacental health can be improved by metformin in a murine diet-induced model of maternal obesity and glucose intolerance.
Hufnagel, Antonia; Fernandez-Twinn, Denise S; Blackmore, Heather L; Ashmore, Thomas J; Heaton, Robert A; Jenkins, Benjamin; Koulman, Albert; Hargreaves, Iain P; Aiken, Catherine E; Ozanne, Susan E.
Affiliation
  • Hufnagel A; Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke's Hospital, University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Cambridge, UK.
  • Fernandez-Twinn DS; Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke's Hospital, University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Cambridge, UK.
  • Blackmore HL; Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke's Hospital, University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Cambridge, UK.
  • Ashmore TJ; Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke's Hospital, University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Cambridge, UK.
  • Heaton RA; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
  • Jenkins B; Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke's Hospital, University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Cambridge, UK.
  • Koulman A; Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Addenbrooke's Hospital, University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Cambridge, UK.
  • Hargreaves IP; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
  • Aiken CE; Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.
  • Ozanne SE; National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK.
J Physiol ; 600(4): 903-919, 2022 02.
Article in En | MEDLINE | ID: mdl-34505282
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Full text: 1 Database: MEDLINE Main subject: Glucose Intolerance / Obesity, Maternal / Metformin Type of study: Prognostic_studies Limits: Animals / Female / Humans / Pregnancy Language: En Year: 2022 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Glucose Intolerance / Obesity, Maternal / Metformin Type of study: Prognostic_studies Limits: Animals / Female / Humans / Pregnancy Language: En Year: 2022 Type: Article