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Genomic profiling of a randomized trial of interferon-α vs hydroxyurea in MPN reveals mutation-specific responses.
Knudsen, Trine Alma; Skov, Vibe; Stevenson, Kristen; Werner, Lillian; Duke, William; Laurore, Charles; Gibson, Christopher J; Nag, Anwesha; Thorner, Aaron R; Wollison, Bruce; Hansen, Dennis Lund; Ellervik, Christina; El Fassi, Daniel; de Stricker, Karin; Ocias, Lukas Frans; Brabrand, Mette; Bjerrum, Ole Weis; Overgaard, Ulrik Malthe; Frederiksen, Mikael; Kristensen, Thomas Kielsgaard; Kruse, Torben A; Thomassen, Mads; Mourits-Andersen, Torben; Severinsen, Marianne Tang; Stentoft, Jesper; Starklint, Joern; Neuberg, Donna S; Kjaer, Lasse; Larsen, Thomas Stauffer; Hasselbalch, Hans Carl; Lindsley, R Coleman; Mullally, Ann.
Affiliation
  • Knudsen TA; Department of Hematology, Zealand University Hospital, Roskilde, Denmark.
  • Skov V; Department of Hematology, Zealand University Hospital, Roskilde, Denmark.
  • Stevenson K; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA.
  • Werner L; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA.
  • Duke W; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
  • Laurore C; Division of Hematology, Brigham and Women's Hospital, Boston, MA.
  • Gibson CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Nag A; Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA.
  • Thorner AR; Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA.
  • Wollison B; Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA.
  • Hansen DL; Department of Hematology, Odense University Hospital, Odense, Denmark.
  • Ellervik C; Department of Data and Innovation Support, Region Zealand, Soroe, Denmark.
  • El Fassi D; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • de Stricker K; Department of Laboratory Medicine, Boston Children's Hospital, Boston, MA.
  • Ocias LF; Department of Pathology, Harvard Medical School, Boston, MA.
  • Brabrand M; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Bjerrum OW; Department of Hematology, Herlev and Gentofte Hospital, Herlev, Denmark.
  • Overgaard UM; Department of Hematology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Frederiksen M; Department of Pathology, Odense University Hospital, Odense, Denmark.
  • Kristensen TK; Statens Serum Institut, Copenhagen, Denmark.
  • Kruse TA; Department of Hematology, Odense University Hospital, Odense, Denmark.
  • Thomassen M; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Mourits-Andersen T; Department of Hematology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Severinsen MT; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Stentoft J; Department of Hematology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Starklint J; Department of Hematology, Hospital of Southern Jutland, Haderslev, Denmark.
  • Neuberg DS; Department of Pathology, Odense University Hospital, Odense, Denmark.
  • Kjaer L; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
  • Larsen TS; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
  • Hasselbalch HC; Department of Hematology, Hospital of South West Jutland, Esbjerg, Denmark.
  • Lindsley RC; Department of Hematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark.
  • Mullally A; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Blood Adv ; 6(7): 2107-2119, 2022 04 12.
Article in En | MEDLINE | ID: mdl-34507355
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Full text: 1 Database: MEDLINE Main subject: Hydroxyurea / Myeloproliferative Disorders Type of study: Clinical_trials Limits: Humans Language: En Year: 2022 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Hydroxyurea / Myeloproliferative Disorders Type of study: Clinical_trials Limits: Humans Language: En Year: 2022 Type: Article