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Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart.
Sousa Fialho, Maria da Luz; Purnama, Ujang; Dennis, Kaitlyn M J H; Montes Aparicio, Claudia N; Castro-Guarda, Marcos; Massourides, Emmanuelle; Tyler, Damian J; Carr, Carolyn A; Heather, Lisa C.
Affiliation
  • Sousa Fialho MDL; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K.
  • Purnama U; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K.
  • Dennis KMJH; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K.
  • Montes Aparicio CN; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K.
  • Castro-Guarda M; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K.
  • Massourides E; Centre d'Etude des Cellules Souches/I-Stem, INSERM UMR 861, AFM-Téléthon, Corbeil-Essonnes, France.
  • Tyler DJ; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K.
  • Carr CA; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K.
  • Heather LC; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, U.K. lisa.heather@dpag.ox.ac.uk.
Diabetes ; 70(11): 2518-2531, 2021 11.
Article in En | MEDLINE | ID: mdl-34526367
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Full text: 1 Database: MEDLINE Main subject: Pyrazoles / Triazoles / Hypoxia-Inducible Factor 1, alpha Subunit / Diabetic Cardiomyopathies Limits: Animals / Humans Language: En Year: 2021 Type: Article
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Pyrazoles / Triazoles / Hypoxia-Inducible Factor 1, alpha Subunit / Diabetic Cardiomyopathies Limits: Animals / Humans Language: En Year: 2021 Type: Article