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Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice.
Castro, Érique; Vieira, Thayna S; Oliveira, Tiago E; Ortiz-Silva, Milene; Andrade, Maynara L; Tomazelli, Caroline A; Peixoto, Albert S; Sobrinho, Cleyton R; Moreno, Mayara F; Gilio, Gustavo R; Moreira, Rafael J; Guimarães, Raphael C; Perandini, Luiz A; Chimin, Patricia; Reckziegel, Patricia; Moretti, Eduardo H; Steiner, Alexandre A; Laplante, Mathieu; Festuccia, William T.
Affiliation
  • Castro É; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Vieira TS; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Oliveira TE; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Ortiz-Silva M; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Andrade ML; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Tomazelli CA; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Peixoto AS; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Sobrinho CR; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Moreno MF; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Gilio GR; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Moreira RJ; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Guimarães RC; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Perandini LA; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
  • Chimin P; Department of Physical Education, Physical Education and Sports Center, Londrina State University, Parana, Brazil.
  • Reckziegel P; Department of Pharmacology, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Sao Paulo, Brazil.
  • Moretti EH; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil.
  • Steiner AA; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, Sao Paulo, Brazil.
  • Laplante M; Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Université Laval, Quebec, Quebec, Canada.
  • Festuccia WT; Centre de recherche sur le cancer de l'Université Laval, Université Laval, Québec, Quebec, Canada.
Am J Physiol Endocrinol Metab ; 321(5): E592-E605, 2021 11 01.
Article in En | MEDLINE | ID: mdl-34541875
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Full text: 1 Database: MEDLINE Main subject: Adipose Tissue, Brown / Adipocytes / Thermogenesis / Energy Metabolism / Adipose Tissue, White / Mechanistic Target of Rapamycin Complex 2 / Glucose / Acclimatization Type of study: Health_economic_evaluation Limits: Animals Language: En Year: 2021 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Adipose Tissue, Brown / Adipocytes / Thermogenesis / Energy Metabolism / Adipose Tissue, White / Mechanistic Target of Rapamycin Complex 2 / Glucose / Acclimatization Type of study: Health_economic_evaluation Limits: Animals Language: En Year: 2021 Type: Article