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Antibiotics for lower respiratory tract infection in children presenting in primary care in England (ARTIC PC): a double-blind, randomised, placebo-controlled trial.
Little, Paul; Francis, Nick A; Stuart, Beth; O'Reilly, Gilly; Thompson, Natalie; Becque, Taeko; Hay, Alastair D; Wang, Kay; Sharland, Michael; Harnden, Anthony; Yao, Guiqing; Raftery, James; Zhu, Shihua; Little, Joseph; Hookham, Charlotte; Rowley, Kate; Euden, Joanne; Harman, Kim; Coenen, Samuel; Read, Robert C; Woods, Catherine; Butler, Christopher C; Faust, Saul N; Leydon, Geraldine; Wan, Mandy; Hood, Kerenza; Whitehurst, Jane; Richards-Hall, Samantha; Smith, Peter; Thomas, Michael; Moore, Michael; Verheij, Theo.
Affiliation
  • Little P; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK. Electronic address: p.little@soton.ac.uk.
  • Francis NA; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Stuart B; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • O'Reilly G; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Thompson N; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Becque T; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Hay AD; Centre for Academic Primary Care, Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, UK.
  • Wang K; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Sharland M; Institute of Infection and Immunity, St George's University London, London, UK.
  • Harnden A; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Yao G; Biostatistics Research Group, Department of Health Sciences, College of Life Sciences, University of Leicester, Leicester, UK.
  • Raftery J; Health Economics Analysis Team, University of Southampton, Southampton, UK.
  • Zhu S; Health Economics Analysis Team, University of Southampton, Southampton, UK.
  • Little J; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Hookham C; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Rowley K; Centre for Academic Primary Care, Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, UK.
  • Euden J; Centre for Trials Research, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.
  • Harman K; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Coenen S; Department of Family Medicine and Population Health and Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.
  • Read RC; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK; National Institute of Health Research Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Woods C; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Butler CC; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Faust SN; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK; National Institute of Health Research Southampton Clinical Research Facility and Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Leydon G; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Wan M; Evelina Pharmacy, Guy's and St Thomas NHS Foundation Trust, London, UK.
  • Hood K; Centre for Trials Research, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.
  • Whitehurst J; Applied Research Collaboration West Midlands, Coventry, UK.
  • Richards-Hall S; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Smith P; Southampton Statistical Sciences Research Institute, University of Southampton, Southampton, UK.
  • Thomas M; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Moore M; Primary Care Research Centre, Primary Care Population Sciences and Medical Education Unit, University of Southampton, Southampton, UK.
  • Verheij T; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands.
Lancet ; 398(10309): 1417-1426, 2021 10 16.
Article in En | MEDLINE | ID: mdl-34562391
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Full text: 1 Database: MEDLINE Main subject: Respiratory Tract Infections / Amoxicillin / Anti-Bacterial Agents Type of study: Clinical_trials / Guideline Limits: Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Europa Language: En Year: 2021 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Respiratory Tract Infections / Amoxicillin / Anti-Bacterial Agents Type of study: Clinical_trials / Guideline Limits: Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Europa Language: En Year: 2021 Type: Article