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Leveraging external data in the design and analysis of clinical trials in neuro-oncology.
Rahman, Rifaquat; Ventz, Steffen; McDunn, Jon; Louv, Bill; Reyes-Rivera, Irmarie; Polley, Mei-Yin C; Merchant, Fahar; Abrey, Lauren E; Allen, Joshua E; Aguilar, Laura K; Aguilar-Cordova, Estuardo; Arons, David; Tanner, Kirk; Bagley, Stephen; Khasraw, Mustafa; Cloughesy, Timothy; Wen, Patrick Y; Alexander, Brian M; Trippa, Lorenzo.
Affiliation
  • Rahman R; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA, USA. Electronic address: rrahman@bwh.harvard.edu.
  • Ventz S; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T H Chan School of Public Health, Boston, MA, USA.
  • McDunn J; Project Data Sphere, Morrisville, NC, USA.
  • Louv B; Project Data Sphere, Morrisville, NC, USA.
  • Reyes-Rivera I; F Hoffmann-La Roche, Basel, Switzerland.
  • Polley MC; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA.
  • Merchant F; Medicenna Therapeutics, Toronto, ON, Canada.
  • Abrey LE; Novartis, Basel, Switzerland.
  • Allen JE; Chimerix, Durham, NC, USA.
  • Aguilar LK; Candel Therapeutics, Needham, MA, USA.
  • Aguilar-Cordova E; Candel Therapeutics, Needham, MA, USA.
  • Arons D; National Brain Tumor Society, Newton, MA, USA.
  • Tanner K; National Brain Tumor Society, Newton, MA, USA.
  • Bagley S; Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Khasraw M; Department of Neurosurgery, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, NC, USA.
  • Cloughesy T; Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Wen PY; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Harvard T H Chan School of Public Health, Boston, MA, USA.
  • Alexander BM; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA, USA; Foundation Medicine, Cambridge, MA, USA.
  • Trippa L; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T H Chan School of Public Health, Boston, MA, USA.
Lancet Oncol ; 22(10): e456-e465, 2021 10.
Article in En | MEDLINE | ID: mdl-34592195
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Full text: 1 Database: MEDLINE Main subject: Research Design / Brain Neoplasms / Glioblastoma / Controlled Clinical Trials as Topic / Medical Oncology / Neurology / Antineoplastic Agents Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Research Design / Brain Neoplasms / Glioblastoma / Controlled Clinical Trials as Topic / Medical Oncology / Neurology / Antineoplastic Agents Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Year: 2021 Type: Article