An Autopsy Confirmed Neuromyelitis Optica Spectrum Disorder with Extensive Brain White Matter Lesion and Optic Neuritis but Intact Spinal Cord, Clinically Mimicking a Secondary Progressive Multiple Sclerosis-like Course.

Azuma, Fumika; Nokura, Kazuya; Kako, Tetsuharu; Yoshida, Mari; Tatsumi, Shinsui

Azuma, Fumika; Nokura, Kazuya; Kako, Tetsuharu; Yoshida, Mari; Tatsumi, Shinsui.

Affiliation

Azuma F; Department of Neurology, Fujita Health University Bantane Hospital, Japan.
Nokura K; Department of Neurology, Fujita Health University Bantane Hospital, Japan.
Kako T; Department of Neurology, Fujita Health University Bantane Hospital, Japan.
Yoshida M; Aichi Medical University, Institute for Medical Science of Aging, Japan.
Tatsumi S; Department of Neurology, Yao Tokushukai General Hospital, Japan.

Intern Med ; 61(9): 1415-1422, 2022 May 01.

Article in En | MEDLINE | ID: mdl-34645756

Subject(s)

Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis; Neuromyelitis Optica; Optic Neuritis; White Matter; Aquaporin 4; Autoantibodies; Autopsy; Female; Humans; Middle Aged; Multiple Sclerosis/diagnosis; Multiple Sclerosis, Chronic Progressive/complications; Multiple Sclerosis, Chronic Progressive/diagnosis; Multiple Sclerosis, Chronic Progressive/pathology; Neuromyelitis Optica/pathology; Optic Neuritis/complications; Optic Neuritis/etiology; Spinal Cord/diagnostic imaging; Spinal Cord/pathology; White Matter/pathology

Key words

NMO spectrum disorder (NMOSD); anti-aquaporin 4 antibody (NMO-IgG); autopsy examination; multiple sclerosis (MS); neuromyelitis optica (NMO); optic-brain/brainstem type

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Full text: 1 Database: MEDLINE Main subject: Optic Neuritis / Neuromyelitis Optica / Multiple Sclerosis, Chronic Progressive / White Matter / Multiple Sclerosis Type of study: Diagnostic_studies / Etiology_studies Limits: Female / Humans / Middle aged Language: En Year: 2022 Type: Article

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