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Pharmacokinetic and pharmacodynamic assessment of histamine H3 receptor occupancy by enerisant: a human PET study with a novel H3 binding ligand, [11C]TASP457.
Kimura, Yasuyuki; Takahata, Keisuke; Shimazaki, Toshiharu; Kitamura, Soichiro; Seki, Chie; Ikoma, Yoko; Ichise, Masanori; Kawamura, Kazunori; Yamada, Makiko; Zhang, Ming-Rong; Higuchi, Makoto; Nishino, Izumi; Suhara, Tetsuya.
Affiliation
  • Kimura Y; Department of Functional Brain Imaging, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Takahata K; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi, 474-8511, Japan.
  • Shimazaki T; Department of Functional Brain Imaging, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Kitamura S; Taisho Pharmaceutical Co, Ltd. 3-24-1 Takada, Toshima-ku, Tokyo, 170-8633, Japan.
  • Seki C; Department of Functional Brain Imaging, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Ikoma Y; Department of Functional Brain Imaging, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Ichise M; Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
  • Kawamura K; Department of Functional Brain Imaging, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Yamada M; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi, 474-8511, Japan.
  • Zhang MR; Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba, Chiba, 263-8555, Japan.
  • Higuchi M; Department of Functional Brain Imaging, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Nishino I; Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba, Chiba, 263-8555, Japan.
  • Suhara T; Department of Functional Brain Imaging, Institute for Quantum Medical Science , National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan. higuchi.makoto@qst.go.jp.
Eur J Nucl Med Mol Imaging ; 49(4): 1127-1135, 2022 03.
Article in En | MEDLINE | ID: mdl-34651222

Full text: 1 Database: MEDLINE Main subject: Receptors, Histamine H3 / Neuroprotective Agents / Sleep Initiation and Maintenance Disorders / Narcolepsy Type of study: Prognostic_studies Limits: Humans / Male Language: En Year: 2022 Type: Article

Full text: 1 Database: MEDLINE Main subject: Receptors, Histamine H3 / Neuroprotective Agents / Sleep Initiation and Maintenance Disorders / Narcolepsy Type of study: Prognostic_studies Limits: Humans / Male Language: En Year: 2022 Type: Article