Your browser doesn't support javascript.
loading
Concussion and long-term cognitive function among rugby players-The BRAIN Study.
Gallo, Valentina; McElvenny, Damien M; Seghezzo, Giulia; Kemp, Simon; Williamson, Elizabeth; Lu, Kirsty; Mian, Saba; James, Laura; Hobbs, Catherine; Davoren, Donna; Arden, Nigel; Davies, Madeline; Malaspina, Andrea; Loosemore, Michael; Stokes, Keith; Cross, Matthew; Crutch, Sebastian; Zetterberg, Henrik; Pearce, Neil.
Affiliation
  • Gallo V; Centre for Primary Care and Public Health, Queen Mary, University of London, London, UK.
  • McElvenny DM; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Seghezzo G; School of Public Health, Imperial College London, London, UK.
  • Kemp S; Campus Fryslân, University of Groningen, Leeuwarden, the Netherlands.
  • Williamson E; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Lu K; Research Group, Institute of Occupational Medicine, Edinburgh, UK.
  • Mian S; Centre for Occupational and Environmental Health, University of Manchester, Manchester, UK.
  • James L; Centre for Primary Care and Public Health, Queen Mary, University of London, London, UK.
  • Hobbs C; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Davoren D; Rugby Football Union, London, UK.
  • Arden N; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Davies M; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.
  • Malaspina A; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Loosemore M; Centre for Primary Care and Public Health, Queen Mary, University of London, London, UK.
  • Stokes K; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Cross M; Department of Health for Keith Stokes and Madeleine Davies, Department of Psychology for Catherine Hobbs, University of Bath, Bath, UK.
  • Crutch S; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
  • Zetterberg H; Centre for Sport, Exercise & Osteoarthritis Research Versus Arthritis, University of Oxford, Oxford, UK.
  • Pearce N; Department of Health for Keith Stokes and Madeleine Davies, Department of Psychology for Catherine Hobbs, University of Bath, Bath, UK.
Alzheimers Dement ; 18(6): 1164-1176, 2022 06.
Article in En | MEDLINE | ID: mdl-34668650
ABSTRACT

OBJECTIVE:

The BRAIN Study was established to assess the associations between self-reported concussions and cognitive function among retired rugby players.

METHODS:

Former elite-level male rugby union players (50+ years) in England were recruited. Exposure to rugby-related concussion was collected using the BRAIN-Q tool. The primary outcome measure was the Preclinical Alzheimer Cognitive Composite (PACC). Linear regressions were conducted for the association between concussion and PACC score, adjusting for confounders.

RESULTS:

A total of 146 participants were recruited. The mean (standard deviation) length of playing career was 15.8 (5.4) years. A total of 79.5% reported rugby-related concussion(s). No association was found between concussion and PACC (ß -0.03 [95% confidence interval (CI) -1.31, 0.26]). However, participants aged 80+ years reporting 3+ concussions had worse cognitive function than those without concussion (ß -1.04 [95% CI -1.62, -0.47]).

CONCLUSIONS:

Overall there was no association between concussion and cognitive function; however, a significant interaction with age revealed an association in older participants.
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Athletic Injuries / Brain Concussion / Football Limits: Aged / Humans / Male Language: En Year: 2022 Type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Athletic Injuries / Brain Concussion / Football Limits: Aged / Humans / Male Language: En Year: 2022 Type: Article