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Serial single-cell genomics reveals convergent subclonal evolution of resistance as early-stage breast cancer patients progress on endocrine plus CDK4/6 therapy.
Griffiths, Jason I; Chen, Jinfeng; Cosgrove, Patrick A; O'Dea, Anne; Sharma, Priyanka; Ma, Cynthia; Trivedi, Meghna; Kalinsky, Kevin; Wisinski, Kari B; O'Regan, Ruth; Makhoul, Issam; Spring, Laura M; Bardia, Aditya; Adler, Frederick R; Cohen, Adam L; Chang, Jeffrey T; Khan, Qamar J; Bild, Andrea H.
Affiliation
  • Griffiths JI; Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA.
  • Chen J; Department of Mathematics, University of Utah, Salt Lake City, UT, USA.
  • Cosgrove PA; Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA.
  • O'Dea A; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
  • Sharma P; Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA.
  • Ma C; Division of Medical Oncology, University of Kansas Medical Center, Westwood, KS, USA.
  • Trivedi M; Division of Medical Oncology, University of Kansas Medical Center, Westwood, KS, USA.
  • Kalinsky K; Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA.
  • Wisinski KB; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
  • O'Regan R; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
  • Makhoul I; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Carbone Cancer Center, Madison, WI, USA.
  • Spring LM; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Carbone Cancer Center, Madison, WI, USA.
  • Bardia A; Division of Internal Medical Oncology, University of Arkansas for Medical Sciences, Fayetteville, AR, USA.
  • Adler FR; Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA, USA.
  • Cohen AL; Department of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA, USA.
  • Chang JT; Department of Mathematics, University of Utah, Salt Lake City, UT, USA.
  • Khan QJ; School of Biological Sciences, University of Utah, Salt Lake City, UT, USA.
  • Bild AH; Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Nat Cancer ; 2(6): 658-671, 2021 06.
Article in En | MEDLINE | ID: mdl-34712959
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Full text: 1 Database: MEDLINE Main subject: Breast Neoplasms Limits: Female / Humans Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Breast Neoplasms Limits: Female / Humans Language: En Year: 2021 Type: Article