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Inhibition of the cysteinyl leukotriene pathways increases survival of RGCs and reduces microglial activation in ocular hypertension.
Trost, Andrea; Motloch, Karolina; Koller, Andreas; Bruckner, Daniela; Runge, Christian; Schroedl, Falk; Bogner, Barbara; Kaser-Eichberger, Alexandra; Strohmaier, Clemens; Ladek, Anja-Maria; Preishuber-Pfluegl, Julia; Brunner, Susanne Maria; Aigner, Ludwig; Reitsamer, Herbert Anton.
Affiliation
  • Trost A; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria. Electronic address: a.zurl@salk.at.
  • Motloch K; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria.
  • Koller A; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria.
  • Bruckner D; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria.
  • Runge C; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria.
  • Schroedl F; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria; Center for Anatomy and Cell Biology, Institute of Anatomy and Cell Biology - Salzburg, Paracelsus Medical University, Salzburg, Aus
  • Bogner B; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria.
  • Kaser-Eichberger A; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria; Center for Anatomy and Cell Biology, Institute of Anatomy and Cell Biology - Salzburg, Paracelsus Medical University, Salzburg, Aus
  • Strohmaier C; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria; Department of Ophthalmology and Optometry, Johannes Kepler University, Linz, Austria.
  • Ladek AM; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria.
  • Preishuber-Pfluegl J; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria.
  • Brunner SM; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria.
  • Aigner L; Institute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria; Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University Salzburg, Austria.
  • Reitsamer HA; University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University/SALK, 5020, Salzburg, Austria; Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University Salzburg, Austria.
Exp Eye Res ; 213: 108806, 2021 12.
Article in En | MEDLINE | ID: mdl-34715090
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Full text: 1 Database: MEDLINE Main subject: Retinal Ganglion Cells / Ocular Hypertension / Receptors, Leukotriene / Microglia / Leukotriene Antagonists / Receptors, G-Protein-Coupled Type of study: Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Retinal Ganglion Cells / Ocular Hypertension / Receptors, Leukotriene / Microglia / Leukotriene Antagonists / Receptors, G-Protein-Coupled Type of study: Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article