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Melanoma secretion of transforming growth factor-ß2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration.
Cosgarea, I; McConnell, A T; Ewen, T; Tang, D; Hill, D S; Anagnostou, M; Elias, M; Ellis, R A; Murray, A; Spender, L C; Giglio, P; Gagliardi, M; Greenwood, A; Piacentini, M; Inman, G J; Fimia, G M; Corazzari, M; Armstrong, J L; Lovat, P E.
Affiliation
  • Cosgarea I; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • McConnell AT; AMLo Biosciences Ltd, The Biosphere, Newcastle upon Tyne, UK.
  • Ewen T; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Tang D; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Hill DS; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Anagnostou M; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Elias M; Faculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland, UK.
  • Ellis RA; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Murray A; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Spender LC; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Giglio P; AMLo Biosciences Ltd, The Biosphere, Newcastle upon Tyne, UK.
  • Gagliardi M; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Greenwood A; Jacqui Wood Cancer Centre & Nine Wells Hospital and Medical School, University of Dundee, Dundee, UK.
  • Piacentini M; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy.
  • Inman GJ; Department Health Sciences, and Centre for Translational Research on Autoimmune and Allergic Disease (CAAD), University of Piemonte Orientale, Novara, Italy.
  • Fimia GM; Translation and Clinical Research Institute, The Medical School, Newcastle University, Newcastle, UK.
  • Corazzari M; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy.
  • Armstrong JL; Department of Epidemiology, Preclinical Research, and Advanced Diagnostics, National Institute for Infectious Diseases 'L. Spallanzani' IRCCS, Rome, Italy.
  • Lovat PE; CRUK Beatson Institute and Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
Br J Dermatol ; 186(4): 694-704, 2022 04.
Article in En | MEDLINE | ID: mdl-34773645

Full text: 1 Database: MEDLINE Main subject: Skin Neoplasms / Transforming Growth Factor beta2 / Melanoma Limits: Humans Language: En Year: 2022 Type: Article

Full text: 1 Database: MEDLINE Main subject: Skin Neoplasms / Transforming Growth Factor beta2 / Melanoma Limits: Humans Language: En Year: 2022 Type: Article