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Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia.
Fukami, Hirotaka; Morinaga, Jun; Nakagami, Hironori; Hayashi, Hiroki; Okadome, Yusuke; Matsunaga, Eiji; Kadomatsu, Tsuyoshi; Horiguchi, Haruki; Sato, Michio; Sugizaki, Taichi; Kuwabara, Takashige; Miyata, Keishi; Mukoyama, Masashi; Morishita, Ryuichi; Oike, Yuichi.
Affiliation
  • Fukami H; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Morinaga J; Department of Nephrology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Nakagami H; Center for Metabolic Regulation of Healthy Aging (CMHA), Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Hayashi H; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Okadome Y; Department of Nephrology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Matsunaga E; Center for Metabolic Regulation of Healthy Aging (CMHA), Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Kadomatsu T; Department of Health Development and Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Horiguchi H; Department of Health Development and Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Sato M; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Sugizaki T; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Kuwabara T; Department of Nephrology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Miyata K; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Mukoyama M; Center for Metabolic Regulation of Healthy Aging (CMHA), Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Morishita R; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
  • Oike Y; Center for Metabolic Regulation of Healthy Aging (CMHA), Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-0556, Japan.
Cell Rep Med ; 2(11): 100446, 2021 11 16.
Article in En | MEDLINE | ID: mdl-34841293
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Full text: 1 Database: MEDLINE Main subject: Vaccines / Dyslipidemias / Angiopoietin-Like Protein 3 / Hyperlipoproteinemia Type II / Obesity Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Year: 2021 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Vaccines / Dyslipidemias / Angiopoietin-Like Protein 3 / Hyperlipoproteinemia Type II / Obesity Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Year: 2021 Type: Article