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Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin.
Ghanawi, Hanaa; Hennlein, Luisa; Zare, Abdolhossein; Bader, Jakob; Salehi, Saeede; Hornburg, Daniel; Ji, Changhe; Sivadasan, Rajeeve; Drepper, Carsten; Meissner, Felix; Mann, Matthias; Jablonka, Sibylle; Briese, Michael; Sendtner, Michael.
Affiliation
  • Ghanawi H; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97080, Germany.
  • Hennlein L; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97080, Germany.
  • Zare A; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97080, Germany.
  • Bader J; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried82152, Germany.
  • Salehi S; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97080, Germany.
  • Hornburg D; Experimental Systems Immunology, Max Planck Institute of Biochemistry, Martinsried 82152, Germany.
  • Ji C; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97080, Germany.
  • Sivadasan R; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97080, Germany.
  • Drepper C; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97080, Germany.
  • Meissner F; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried82152, Germany.
  • Mann M; Experimental Systems Immunology, Max Planck Institute of Biochemistry, Martinsried 82152, Germany.
  • Jablonka S; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried82152, Germany.
  • Briese M; NNF Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen DK-2200, Denmark.
  • Sendtner M; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97080, Germany.
Nucleic Acids Res ; 49(21): 12284-12305, 2021 12 02.
Article in En | MEDLINE | ID: mdl-34850154
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Full text: 1 Database: MEDLINE Main subject: DNA Damage / Chromatin / Heterogeneous-Nuclear Ribonucleoproteins / DNA Repair / Y-Box-Binding Protein 1 / Motor Neurons Limits: Animals / Humans Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: DNA Damage / Chromatin / Heterogeneous-Nuclear Ribonucleoproteins / DNA Repair / Y-Box-Binding Protein 1 / Motor Neurons Limits: Animals / Humans Language: En Year: 2021 Type: Article