The effects of substrate composition and topography on the characteristics and growth of cell cultures of cochlear fibrocytes.

Mahendrasingam, Shanthini; Osborn, Anya; Israr, Muhammad Zubair; Riasat, Kiran; Gater, Rachel Va; Spano, Andrea; Gogo-Fyneface, Desire; Worrall, Amy J; Furness, David N

Mahendrasingam, Shanthini; Osborn, Anya; Israr, Muhammad Zubair; Riasat, Kiran; Gater, Rachel Va; Spano, Andrea; Gogo-Fyneface, Desire; Worrall, Amy J; Furness, David N.

Affiliation

Mahendrasingam S; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom.
Osborn A; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom.
Israr MZ; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom. Electronic address: mzi4@leicester.ac.uk.
Riasat K; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom.
Gater RV; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom.
Spano A; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom.
Gogo-Fyneface D; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom.
Worrall AJ; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom. Electronic address: a.j.worrall1@keele.ac.uk.
Furness DN; School of Life Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom. Electronic address: d.n.furness@keele.ac.uk.

Hear Res ; 415: 108427, 2022 03 01.

Article in En | MEDLINE | ID: mdl-34999290

Subject(s)

Cochlea; Ear, Inner; Animals; Cell Culture Techniques; Cochlea/metabolism; Ear, Inner/metabolism; Hearing; Mice; Sodium-Potassium-Exchanging ATPase/metabolism

Key words

2D vs 3D cell cultures; Fibrocyte replacement therapy; Hydrogels; Metabolic hearing loss

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