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Discovery of a dual-action small molecule that improves neuropathological features of Alzheimer's disease mice.
Park, Min Hee; Park, Kang Ho; Choi, Byung Jo; Han, Wan Hui; Yoon, Hee Ji; Jung, Hye Yoon; Lee, Jihoon; Song, Im-Sook; Lim, Dong Yu; Choi, Min-Koo; Lee, Yang-Ha; Park, Cheol-Min; Wang, Ming; Jo, Jihoon; Kim, Hee-Jin; Kim, Seung Hyun; Schuchman, Edward H; Jin, Hee Kyung; Bae, Jae-Sung.
Affiliation
  • Park MH; KNU Alzheimer's Disease Research Institute, Kyungpook National University, Daegu 41566, South Korea.
  • Park KH; Department of Physiology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
  • Choi BJ; KNU Alzheimer's Disease Research Institute, Kyungpook National University, Daegu 41566, South Korea.
  • Han WH; Department of Physiology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
  • Yoon HJ; KNU Alzheimer's Disease Research Institute, Kyungpook National University, Daegu 41566, South Korea.
  • Jung HY; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, South Korea.
  • Lee J; KNU Alzheimer's Disease Research Institute, Kyungpook National University, Daegu 41566, South Korea.
  • Song IS; Department of Physiology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
  • Lim DY; KNU Alzheimer's Disease Research Institute, Kyungpook National University, Daegu 41566, South Korea.
  • Choi MK; Department of Physiology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
  • Lee YH; KNU Alzheimer's Disease Research Institute, Kyungpook National University, Daegu 41566, South Korea.
  • Park CM; Department of Physiology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
  • Wang M; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, South Korea.
  • Jo J; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, South Korea.
  • Kim HJ; College of Pharmacy, Dankook University, Cheon-an 31116, South Korea.
  • Kim SH; College of Pharmacy, Dankook University, Cheon-an 31116, South Korea.
  • Schuchman EH; Department of Chemistry, Ulsan National Institute of Science and Technology, Ulsan 44919, South Korea.
  • Jin HK; Department of Chemistry, Ulsan National Institute of Science and Technology, Ulsan 44919, South Korea.
  • Bae JS; BioMedical Sciences Graduate Program, Chonnam National University, Hwasun 58128, South Korea.
Proc Natl Acad Sci U S A ; 119(3)2022 01 18.
Article in En | MEDLINE | ID: mdl-35027452
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Full text: 1 Database: MEDLINE Main subject: Alzheimer Disease / Neuropathology Type of study: Prognostic_studies Limits: Animals Language: En Year: 2022 Type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Alzheimer Disease / Neuropathology Type of study: Prognostic_studies Limits: Animals Language: En Year: 2022 Type: Article