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RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency.
Stok, Jorn E; Oosenbrug, Timo; Ter Haar, Laurens R; Gravekamp, Dennis; Bromley, Christian P; Zelenay, Santiago; Reis e Sousa, Caetano; van der Veen, Annemarthe G.
Affiliation
  • Stok JE; Department of Immunology, Leiden University Medical Centre, Leiden, The Netherlands.
  • Oosenbrug T; Department of Immunology, Leiden University Medical Centre, Leiden, The Netherlands.
  • Ter Haar LR; Department of Immunology, Leiden University Medical Centre, Leiden, The Netherlands.
  • Gravekamp D; Department of Immunology, Leiden University Medical Centre, Leiden, The Netherlands.
  • Bromley CP; Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, UK.
  • Zelenay S; Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, UK.
  • Reis e Sousa C; Immunobiology Laboratory, The Francis Crick Institute, London, UK.
  • van der Veen AG; Department of Immunology, Leiden University Medical Centre, Leiden, The Netherlands.
EMBO J ; 41(6): e109760, 2022 03 15.
Article in En | MEDLINE | ID: mdl-35156720
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Full text: 1 Database: MEDLINE Main subject: RNA Helicases / Autoimmune Diseases of the Nervous System / Nervous System Malformations Limits: Humans Language: En Year: 2022 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: RNA Helicases / Autoimmune Diseases of the Nervous System / Nervous System Malformations Limits: Humans Language: En Year: 2022 Type: Article