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The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Wang, Lawrence T; Hurlburt, Nicholas K; Schön, Arne; Flynn, Barbara J; Flores-Garcia, Yevel; Pereira, Lais S; Kiyuka, Patience K; Dillon, Marlon; Bonilla, Brian; Zavala, Fidel; Idris, Azza H; Francica, Joseph R; Pancera, Marie; Seder, Robert A.
Affiliation
  • Wang LT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Hurlburt NK; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Schön A; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Flynn BJ; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Flores-Garcia Y; Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
  • Pereira LS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kiyuka PK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Dillon M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Bonilla B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Zavala F; Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
  • Idris AH; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Francica JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Pancera M; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address: mpancera@fredhutch.org.
  • Seder RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: rseder@mail.nih.gov.
Cell Rep ; 38(7): 110367, 2022 02 15.
Article in En | MEDLINE | ID: mdl-35172158
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Full text: 1 Database: MEDLINE Main subject: Protozoan Proteins / Malaria, Falciparum / Immunoglobulin Light Chains / Repetitive Sequences, Amino Acid / Antibodies, Monoclonal Limits: Adolescent / Adult / Animals / Female / Humans / Middle aged Language: En Year: 2022 Type: Article
Fulltext
Print
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PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Protozoan Proteins / Malaria, Falciparum / Immunoglobulin Light Chains / Repetitive Sequences, Amino Acid / Antibodies, Monoclonal Limits: Adolescent / Adult / Animals / Female / Humans / Middle aged Language: En Year: 2022 Type: Article