E-series resolvin metabolome, biosynthesis and critical role of stereochemistry of specialized pro-resolving mediators (SPMs) in inflammation-resolution: Preparing SPMs for long COVID-19, human clinical trials, and targeted precision nutrition.

Serhan, Charles N; Libreros, Stephania; Nshimiyimana, Robert

Serhan, Charles N; Libreros, Stephania; Nshimiyimana, Robert.

Affiliation

Serhan CN; Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address: cserhan@bwh.harvard.edu.
Libreros S; Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Nshimiyimana R; Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Semin Immunol ; 59: 101597, 2022 01.

Article in En | MEDLINE | ID: mdl-35227568

Subject(s)

COVID-19; Eicosapentaenoic Acid; Animals; Humans; Docosahexaenoic Acids/therapeutic use; Eicosapentaenoic Acid/therapeutic use; Inflammation; Inflammation Mediators/metabolism; Metabolome; Pandemics; Post-Acute COVID-19 Syndrome; Clinical Trials as Topic

Key words

Docosahexaenoic acid (DHA); Eicosapentaenoic acid (EPA); Human phagocytes; M2 macrophages; Neutrophils; Omega-3 polyunsaturated fatty acids

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Full text: 1 Database: MEDLINE Main subject: Eicosapentaenoic Acid / COVID-19 Limits: Animals / Humans Language: En Year: 2022 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Eicosapentaenoic Acid / COVID-19 Limits: Animals / Humans Language: En Year: 2022 Type: Article