ABSTRACT
Background:
Seropositivity among
health-care
workers (HCWs) may help in better
understanding of the
immune response after COVID-19
infection.
Objectives:
To estimate seropositivity among HCWs and to compare available variables with seropositivity to understand the factors affecting seropositivity. Materials and
Methods:
A serosurveillance among HCWs was carried out using
population proportion sampling during the second half of October 2020 in the city of Ahmedabad using the Covid-Kavach (
immunoglobulin G [
IgG]
ELISA Antibody testing kit). Simple proportions and appropriate statistical tests were used as needed.
Results:
As on October' 2020, HCWs in Ahmedabad demonstrated a seropositivity of 20.84% (95%
confidence interval [CI] 19.00-22.81%). Seropositivity among HCWs was lower than that of the general
population (24.20%) which was estimated as part of the same study.
Female HCWs had higher seropositivity 22.14% (95% CI 19.74-24.74%) as compared to 18.82% (95% CI 16.06-21.93%) among
male HCWs and the difference was statistically not significant (Z = 1.66, P = 0.097).
Age groups with increasing age show increasing trend in the seropositivity among HCWs.
Conclusion:
As on October 2020, with 20.84% seropositivity among HCWs in Ahmedabad, one in every five HCW already demonstrate
IgG antibodies against
severe acute respiratory syndrome-
coronavirus-2. Further scientific studies on seropositivity and the factors affecting the seropositivity may be carried out to uncover more details of immune reaction after COVID-19
infection.
