Inhibition of PIKfyve Ameliorates the Proliferation and Migration of Vascular Smooth Muscle Cells and Vascular Intima Hyperplasia By Reducing mTORC1 Activity.

Gu, Min; Wang, Zhen; Feng, Feifei; Yang, Yongjian; Sun, Xiongshan; Yang, Dachun

Gu, Min; Wang, Zhen; Feng, Feifei; Yang, Yongjian; Sun, Xiongshan; Yang, Dachun.

Affiliation

Gu M; Department of Cardiology, The General Hospital of Western Theater Command, Chengdu, Sichuan, China.

J Cardiovasc Pharmacol ; 79(5): 739-748, 2022 05 01.

Article in En | MEDLINE | ID: mdl-35275098

Subject(s)

Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Animals; Becaplermin/pharmacology; Cell Movement; Cell Proliferation; Cells, Cultured; Glucose/metabolism; Hyperplasia/metabolism; Hyperplasia/pathology; Mammals; Mechanistic Target of Rapamycin Complex 1/metabolism; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular/metabolism; Myocytes, Smooth Muscle/metabolism; Neointima/metabolism; Neointima/pathology; Phosphatidylinositol 3-Kinases/metabolism; Tunica Intima

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Full text: 1 Database: MEDLINE Main subject: Myocytes, Smooth Muscle / Muscle, Smooth, Vascular Type of study: Prognostic_studies Limits: Animals Language: En Year: 2022 Type: Article

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