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An allosteric HTRA1-calpain 2 complex with restricted activation profile.
Rey, Juliana; Breiden, Maike; Lux, Vanda; Bluemke, Anika; Steindel, Maike; Ripkens, Kamilla; Möllers, Bastian; Bravo Rodriguez, Kenny; Boisguerin, Prisca; Volkmer, Rudolf; Mieres-Perez, Joel; Clausen, Tim; Sanchez-Garcia, Elsa; Ehrmann, Michael.
Affiliation
  • Rey J; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Breiden M; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Lux V; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Bluemke A; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Steindel M; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Ripkens K; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Möllers B; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Bravo Rodriguez K; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Boisguerin P; PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, 34295 Montpellier Cedex 5, France.
  • Volkmer R; Institut für Medizinische Immunologie, Charité - Universitätsmedizin Berlin, 10115 Berlin, Germany.
  • Mieres-Perez J; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Clausen T; Research Institute of Molecular Pathology - IMP, 1030 Vienna, Austria.
  • Sanchez-Garcia E; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
  • Ehrmann M; Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitaetsstrasse, 45141 Essen, Germany.
Proc Natl Acad Sci U S A ; 119(14): e2113520119, 2022 04 05.
Article in En | MEDLINE | ID: mdl-35349341
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Full text: 1 Database: MEDLINE Main subject: Serine Endopeptidases / Calpain Language: En Year: 2022 Type: Article
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Serine Endopeptidases / Calpain Language: En Year: 2022 Type: Article