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Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling.
Li, Zhihui; Kwon, So Mee; Li, Daochuan; Li, Linhao; Peng, Xiwei; Zhang, Junran; Sueyoshi, Tatsuya; Raufman, Jean-Pierre; Negishi, Masahiko; Wang, Xin Wei; Wang, Hongbing.
Affiliation
  • Li Z; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
  • Kwon SM; Laboratory of Human Carcinogenesis, and Liver Cancer Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Li D; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
  • Li L; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
  • Peng X; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
  • Zhang J; Department of Radiation Oncology, The Ohio State University James Comprehensive Cancer Center and College of Medicine, Ohio, USA.
  • Sueyoshi T; Pharmacogenetics Section, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.
  • Raufman JP; Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Office of Research and Development, Biomedical Laboratory Research and Development, VA Maryland Healthcare System, Baltimore, Maryland, USA.
  • Negishi M; Pharmacogenetics Section, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA.
  • Wang XW; Laboratory of Human Carcinogenesis, and Liver Cancer Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Wang H; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA. Electronic address: hongbing.wang@rx.umaryland.edu.
J Biol Chem ; 298(5): 101885, 2022 05.
Article in En | MEDLINE | ID: mdl-35367211
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Full text: 1 Database: MEDLINE Main subject: Erythropoietin / Carcinoma, Hepatocellular / Constitutive Androstane Receptor / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2022 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Erythropoietin / Carcinoma, Hepatocellular / Constitutive Androstane Receptor / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2022 Type: Article