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Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators.
Clark, Jennifer M; Salgado-Polo, Fernando; Macdonald, Simon J F; Barrett, Tim N; Perrakis, Anastassis; Jamieson, Craig.
Affiliation
  • Clark JM; Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom.
  • Salgado-Polo F; Oncode Institute and Division of Biochemistry, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.
  • Macdonald SJF; Medicines Design, GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Barrett TN; Medicines Design, GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Perrakis A; Oncode Institute and Division of Biochemistry, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.
  • Jamieson C; Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom.
J Med Chem ; 65(8): 6338-6351, 2022 04 28.
Article in En | MEDLINE | ID: mdl-35440138
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Full text: 1 Database: MEDLINE Main subject: Phosphoric Diester Hydrolases / Neoplasms Limits: Humans Language: En Year: 2022 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Phosphoric Diester Hydrolases / Neoplasms Limits: Humans Language: En Year: 2022 Type: Article