Electrostatic Interaction with the Bacterial Cell Envelope Tunes the Lytic Activity of Two Novel Peptidoglycan Hydrolases.

Wysocka, Alicja; Lezniak, Lukasz; Jagielska, Elzbieta; Sabala, Izabela

Wysocka, Alicja; Lezniak, Lukasz; Jagielska, Elzbieta; Sabala, Izabela.

Affiliation

Wysocka A; International Institute of Molecular and Cell Biologygrid.419362.b in Warsaw, Warsaw, Poland.
Lezniak L; International Institute of Molecular and Cell Biologygrid.419362.b in Warsaw, Warsaw, Poland.
Jagielska E; International Institute of Molecular and Cell Biologygrid.419362.b in Warsaw, Warsaw, Poland.
Sabala I; Mossakowski Medical Research Institute Polish Academy of Sciences, Warsaw, Poland.

Microbiol Spectr ; 10(3): e0045522, 2022 06 29.

Article in En | MEDLINE | ID: mdl-35467396

Subject(s)

N-Acetylmuramoyl-L-alanine Amidase; Teichoic Acids; Anti-Bacterial Agents/therapeutic use; Bacteria/metabolism; Cell Wall/metabolism; Hydrolases/metabolism; N-Acetylmuramoyl-L-alanine Amidase/metabolism; Peptidoglycan/metabolism; Static Electricity; Teichoic Acids/metabolism

Key words

Staphylococcus; Staphylococcus aureus; cell wall; electrostatics; enzybiotics; hydrolase; net charge; peptidoglycan

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Full text: 1 Database: MEDLINE Main subject: Teichoic Acids / N-Acetylmuramoyl-L-alanine Amidase Type of study: Prognostic_studies Language: En Year: 2022 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Teichoic Acids / N-Acetylmuramoyl-L-alanine Amidase Type of study: Prognostic_studies Language: En Year: 2022 Type: Article