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First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement.
Herp, Daniel; Ridinger, Johannes; Robaa, Dina; Shinsky, Stephen A; Schmidtkunz, Karin; Yesiloglu, Talha Z; Bayer, Theresa; Steimbach, Raphael R; Herbst-Gervasoni, Corey J; Merz, Annika; Romier, Christophe; Sehr, Peter; Gunkel, Nikolas; Miller, Aubry K; Christianson, David W; Oehme, Ina; Sippl, Wolfgang; Jung, Manfred.
Affiliation
  • Herp D; Institute of Pharmaceutical Sciences, University of Freiburg, Albertstraße 25, 79104, Freiburg, Germany.
  • Ridinger J; Hopp Children's Cancer Center Heidelberg (KiTZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Robaa D; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Shinsky SA; German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Schmidtkunz K; Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120, Halle (Saale)Halle/Saale, Germany.
  • Yesiloglu TZ; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania, 19104-6323, USA.
  • Bayer T; Institute of Pharmaceutical Sciences, University of Freiburg, Albertstraße 25, 79104, Freiburg, Germany.
  • Steimbach RR; Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120, Halle (Saale)Halle/Saale, Germany.
  • Herbst-Gervasoni CJ; Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120, Halle (Saale)Halle/Saale, Germany.
  • Merz A; German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Romier C; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania, 19104-6323, USA.
  • Sehr P; Institute of Pharmaceutical Sciences, University of Freiburg, Albertstraße 25, 79104, Freiburg, Germany.
  • Gunkel N; Université de Strasbourg, CNRS, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire, UMR 7104, U 1258, 67404, Illkirch, France.
  • Miller AK; IGBMC, Department of Integrated Structural Biology, 1 rue Laurent Fries, B.P. 10142, 67404, Illkirch Cedex, France.
  • Christianson DW; Chemical Biology Core Facility, European Molecular Biology Laboratory, 69117, Heidelberg, Germany.
  • Oehme I; German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Sippl W; Cancer Drug Development Group, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Jung M; German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Chembiochem ; 23(14): e202200180, 2022 07 19.
Article in En | MEDLINE | ID: mdl-35608330
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Full text: 1 Database: MEDLINE Main subject: Spermidine / Neuroblastoma Limits: Humans Language: En Year: 2022 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Spermidine / Neuroblastoma Limits: Humans Language: En Year: 2022 Type: Article