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Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.
Dzamukova, Maria; Brunner, Tobias M; Miotla-Zarebska, Jadwiga; Heinrich, Frederik; Brylka, Laura; Mashreghi, Mir-Farzin; Kusumbe, Anjali; Kühn, Ralf; Schinke, Thorsten; Vincent, Tonia L; Löhning, Max.
Affiliation
  • Dzamukova M; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Centre (DRFZ), a Leibniz Institute, Berlin, Germany. maria.dzamukova@drfz.de.
  • Brunner TM; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. maria.dzamukova@drfz.de.
  • Miotla-Zarebska J; Pitzer Laboratory of Osteoarthritis Research, German Rheumatism Research Centre (DRFZ), a Leibniz Institute, Berlin, Germany.
  • Heinrich F; Experimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Brylka L; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
  • Mashreghi MF; Therapeutic Gene Regulation, Regine von Ramin Lab Molecular Rheumatology, German Rheumatism Research Centre (DRFZ), a Leibniz Institute, Berlin, Germany.
  • Kusumbe A; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Kühn R; Therapeutic Gene Regulation, Regine von Ramin Lab Molecular Rheumatology, German Rheumatism Research Centre (DRFZ), a Leibniz Institute, Berlin, Germany.
  • Schinke T; BIH Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Vincent TL; Tissue and Tumour Microenvironments Group, University of Oxford, Oxford, UK.
  • Löhning M; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
Nat Commun ; 13(1): 3059, 2022 06 01.
Article in En | MEDLINE | ID: mdl-35650194
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Full text: 1 Database: MEDLINE Main subject: Stress, Mechanical / Calcification, Physiologic / Neovascularization, Physiologic Type of study: Prognostic_studies Limits: Adolescent / Humans Language: En Year: 2022 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Stress, Mechanical / Calcification, Physiologic / Neovascularization, Physiologic Type of study: Prognostic_studies Limits: Adolescent / Humans Language: En Year: 2022 Type: Article