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Rescue of lysosomal function as therapeutic strategy for SPG15 hereditary spastic paraplegia.
Vantaggiato, Chiara; Orso, Genny; Guarato, Giulia; Brivio, Francesca; Napoli, Barbara; Panzeri, Elena; Masotti, Simona; Santorelli, Filippo Maria; Lamprou, Maria; Gumeni, Sentiljana; Clementi, Emilio; Bassi, Maria Teresa.
Affiliation
  • Vantaggiato C; Scientific Institute IRCCS E. Medea, Laboratory of Molecular Biology, 23842 Bosisio Parini, Lecco, Italy.
  • Orso G; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Largo E. Meneghetti 2, Padova, Italy.
  • Guarato G; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Largo E. Meneghetti 2, Padova, Italy.
  • Brivio F; Scientific Institute IRCCS E. Medea, Laboratory of Molecular Biology, 23842 Bosisio Parini, Lecco, Italy.
  • Napoli B; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Largo E. Meneghetti 2, Padova, Italy.
  • Panzeri E; Scientific Institute IRCCS E. Medea, Laboratory of Molecular Biology, 23842 Bosisio Parini, Lecco, Italy.
  • Masotti S; Scientific Institute IRCCS E. Medea, Laboratory of Molecular Biology, 23842 Bosisio Parini, Lecco, Italy.
  • Santorelli FM; Department of Molecular Medicine, IRCCS Stella Maris Foundation, Calambrone, 56128 Pisa, Italy.
  • Lamprou M; Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Athens 15784, Greece.
  • Gumeni S; Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Athens 15784, Greece.
  • Clementi E; Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco, 'Luigi Sacco' University Hospital, Università di Milano, Milan, Italy.
  • Bassi MT; Scientific Institute IRCCS E. Medea, Laboratory of Molecular Biology, 23842 Bosisio Parini, Lecco, Italy.
Brain ; 146(3): 1103-1120, 2023 03 01.
Article in En | MEDLINE | ID: mdl-36029068
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Full text: 1 Database: MEDLINE Main subject: Spastic Paraplegia, Hereditary / Carrier Proteins Limits: Humans Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Spastic Paraplegia, Hereditary / Carrier Proteins Limits: Humans Language: En Year: 2023 Type: Article