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Impaired Interleukin-15 Signaling via BMPR2 Loss Drives Natural Killer Cell Deficiency and Pulmonary Hypertension.
Hilton, L Rhiannon; Rätsep, Matthew T; VandenBroek, M Martin; Jafri, Salema; Laverty, Kimberly J; Mitchell, Melissa; Theilmann, Anne L; Smart, James A; Hawke, Lindsey G; Moore, Stephen D; Renaud, Stephen J; Soares, Michael J; Morrell, Nicholas W; Ormiston, Mark L.
Affiliation
  • Hilton LR; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
  • Rätsep MT; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
  • VandenBroek MM; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
  • Jafri S; Department of Medicine, University of Cambridge, Cambridge, United Kingdom (S.J., S.D.M., N.W.M.).
  • Laverty KJ; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
  • Mitchell M; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
  • Theilmann AL; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
  • Smart JA; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
  • Hawke LG; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
  • Moore SD; Department of Medicine, University of Cambridge, Cambridge, United Kingdom (S.J., S.D.M., N.W.M.).
  • Renaud SJ; Department of Anatomy and Cell Biology, Western University, London, Canada (S.J.R.).
  • Soares MJ; Departments of Pathology and Laboratory Medicine and Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City (M.J.S.).
  • Morrell NW; Department of Medicine, University of Cambridge, Cambridge, United Kingdom (S.J., S.D.M., N.W.M.).
  • Ormiston ML; Departments of Biomedical and Molecular Sciences, Medicine and Surgery, Queen's University, Kingston, Canada (L.B.H., M.T.R., M.M.V., K.J.L., M.M., A.L.T., J.A.S., L.G.H., M.L.O.).
Hypertension ; 79(11): 2493-2504, 2022 11.
Article in En | MEDLINE | ID: mdl-36043416
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Full text: 1 Database: MEDLINE Main subject: GATA2 Deficiency / Pulmonary Arterial Hypertension / Hypertension, Pulmonary Type of study: Etiology_studies Limits: Animals / Female / Humans / Male Language: En Year: 2022 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: GATA2 Deficiency / Pulmonary Arterial Hypertension / Hypertension, Pulmonary Type of study: Etiology_studies Limits: Animals / Female / Humans / Male Language: En Year: 2022 Type: Article