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Multi-omics analysis identifies rare variation in leptin/PPAR gene sets and hypermethylation of ABCG1 contribute to antipsychotics-induced metabolic syndromes.
Zhou, Wei; Sun, Jing; Huai, Cong; Liu, Yunxi; Chen, Luan; Yi, Zhenghui; Lv, Qinyu; Song, Chuanfu; Zhu, Wenli; Liu, Chuanxin; Weng, Saizheng; Wu, Hao; Sun, Yidan; Zhang, Runshuai; Wu, Lianfeng; Li, Mo; Zhu, Jinhang; Zhang, Yingtian; Wei, Muyun; Guo, Yujian; Huang, Sijia; Zhang, Na; Shen, Ruoxi; Zhang, Ying; Du, Huihui; Huang, Hailiang; He, Lin; Sun, Xiaofang; Shen, Lu; Qin, Shengying.
Affiliation
  • Zhou W; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Sun J; Neurobiology & Mitochondrial Key Laboratory, School of Pharmacy, Jiangsu University, Zhenjiang, China.
  • Huai C; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Liu Y; Neurobiology & Mitochondrial Key Laboratory, School of Pharmacy, Jiangsu University, Zhenjiang, China.
  • Chen L; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Yi Z; Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Lv Q; Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Song C; The Fourth People's Hospital of Wuhu, Wuhu, China.
  • Zhu W; The Fourth People's Hospital of Wuhu, Wuhu, China.
  • Liu C; Jining Medical University, Department of Psychiatry, School of Mental Health, Psychiatry Genetic Lab PSYG Lab, Jining, China.
  • Weng S; Fuzhou Neuro-Psychiatric Hospital affiliated to Fujian Medical University, Fuzhou, China.
  • Wu H; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Sun Y; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Zhang R; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
  • Wu L; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
  • Li M; Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, Zhejiang Province, China.
  • Zhu J; Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
  • Zhang Y; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
  • Wei M; Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, Zhejiang Province, China.
  • Guo Y; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Huang S; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Zhang N; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Shen R; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Zhang Y; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Du H; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Huang H; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • He L; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Sun X; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Shen L; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.
  • Qin S; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Mol Psychiatry ; 27(12): 5195-5205, 2022 12.
Article in En | MEDLINE | ID: mdl-36065016
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Full text: 1 Database: MEDLINE Main subject: Antipsychotic Agents / Leptin / Metabolic Syndrome / Peroxisome Proliferator-Activated Receptors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2022 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Antipsychotic Agents / Leptin / Metabolic Syndrome / Peroxisome Proliferator-Activated Receptors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2022 Type: Article