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The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations.
Soria-Bretones, Isabel; Thu, Kelsie L; Silvester, Jennifer; Cruickshank, Jennifer; El Ghamrasni, Samah; Ba-Alawi, Wail; Fletcher, Graham C; Kiarash, Reza; Elliott, Mitchell J; Chalmers, Jordan J; Elia, Andrea C; Cheng, Albert; Rose, April A N; Bray, Mark R; Haibe-Kains, Benjamin; Mak, Tak W; Cescon, David W.
Affiliation
  • Soria-Bretones I; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Thu KL; Segal Cancer Centre and Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada.
  • Silvester J; Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, Canada.
  • Cruickshank J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • El Ghamrasni S; Keenan Research Centre for Biomedical Sciences, St. Michael's Hospital , Toronto,, ON, Canada.
  • Ba-Alawi W; Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Fletcher GC; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Kiarash R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Elliott MJ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Chalmers JJ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Elia AC; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Cheng A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Rose AAN; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Bray MR; Department of Medicine, University of Toronto, Toronto , ON, Canada.
  • Haibe-Kains B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Mak TW; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Cescon DW; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Sci Adv ; 8(36): eabq4293, 2022 09 09.
Article in En | MEDLINE | ID: mdl-36070391
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Full text: 1 Database: MEDLINE Main subject: M Phase Cell Cycle Checkpoints / Neoplasms Type of study: Prognostic_studies Language: En Year: 2022 Type: Article
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PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: M Phase Cell Cycle Checkpoints / Neoplasms Type of study: Prognostic_studies Language: En Year: 2022 Type: Article