Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022.
Euro Surveill
; 27(37)2022 09.
Article
in En
| MEDLINE
| ID: mdl-36111556
ABSTRACT
We report an emergence and increase in poliovirus type 2 detection via routine wastewater surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April and July 2022. Sequencing showed genetic linkage among isolates and accumulation of mutations over time, with two isolates defined as vaccine-derived polioviruses (VDPV). This demonstrates the emergence and potential circulation of type 2 VDPV in a high-income country with high vaccine coverage and underscores the importance of routine wastewater surveillance during the polio eradication.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Poliomyelitis
/
Poliovirus
Limits:
Humans
Language:
En
Year:
2022
Type:
Article