Side Effects of COVID-19 Vaccines in Patients with Inflammatory Bowel Disease in Japan.
Dig Dis Sci
; 68(2): 564-570, 2023 02.
Article
in En
| MEDLINE
| ID: mdl-36178566
ABSTRACT
BACKGROUND:
Patients with inflammatory bowel disease (IBD) are recommended to receive the coronavirus disease 2019 (COVID-19) vaccine. However, a recent survey showed that patients with IBD are more hesitant to receive the vaccine than the general population. Detailed information on the side effects of the COVID-19 vaccine is necessary to encourage vaccination among patients with IBD.AIM:
To investigate the frequency of side effects following COVID-19 vaccination in patients with IBD in Japan. STUDYDESIGN:
a cross-sectional survey was conducted using a questionnaire administered to adult patients with IBD in a tertiary medical facility.RESULTS:
Among the participants who answered the questionnaire, 92.6%, 91.5%, and 41.5% of the participants had received their first, second, and third doses of the COVID-19 vaccine, respectively. Of the vaccinated participants, 88.3%, 86.3%, and 89.0% experienced side effects after receiving the first, second, and third doses of the vaccine, respectively. The incidences of fever, chills, and headaches were significantly higher among female participants than among male participants (p < 0.05). However, the frequencies of most side effects were comparable between the BNT162b2 mRNA and mRNA-1273 vaccines.CONCLUSION:
The findings of our survey can help encourage patients with IBD to receive the COVID-19 vaccine.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Inflammatory Bowel Diseases
/
Drug-Related Side Effects and Adverse Reactions
/
COVID-19
Type of study:
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
En
Year:
2023
Type:
Article