Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-&#954;B pathway.

Zhu, Yanhui; Han, Qianqian; Wang, Lei; Wang, Baiyan; Chen, Jianshuang; Cai, Bangrong; Wu, Can; Zhu, Xiali; Liu, Fugang; Han, Deen; Dong, Haoran; Jia, Yongyan; Liu, Yalin

Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway.

Zhu, Yanhui; Han, Qianqian; Wang, Lei; Wang, Baiyan; Chen, Jianshuang; Cai, Bangrong; Wu, Can; Zhu, Xiali; Liu, Fugang; Han, Deen; Dong, Haoran; Jia, Yongyan; Liu, Yalin.

Affiliation

Zhu Y; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: judy202426@126.com.
Han Q; School of Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: hanqianll@hactcm.edu.cn.
Wang L; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: 838133668@qq.com.
Wang B; School of Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: baiyanw@hactcm.edu.cn.
Chen J; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: 511447685@qq.com.
Cai B; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: cbr2018@hactcm.edu.cn.
Wu C; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: wucan_bz@hactcm.edu.cn.
Zhu X; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: zhuxiali1980@126.com.
Liu F; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: 13526585635@163.com.
Han D; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: handn@163.com.
Dong H; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: haoranxc@163.com.
Jia Y; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: hnzyjyy@126.com.
Liu Y; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China. Electronic address: liuyalin_1984@163.com.

J Ethnopharmacol ; 301: 115763, 2023 Jan 30.

Article in En | MEDLINE | ID: mdl-36183949

Subject(s)

Acute Lung Injury; COVID-19; Influenza A Virus, H1N1 Subtype; Mice; Animals; NF-kappa B/metabolism; Toll-Like Receptor 4/metabolism; Lipopolysaccharides/toxicity; Myeloid Differentiation Factor 88/metabolism; Neutrophils; Tumor Necrosis Factor-alpha/metabolism; Influenza A Virus, H1N1 Subtype/metabolism; Interleukin-6/metabolism; Myeloid Cell Leukemia Sequence 1 Protein/metabolism; Myeloid Cell Leukemia Sequence 1 Protein/therapeutic use; Acute Lung Injury/chemically induced; Acute Lung Injury/drug therapy; Acute Lung Injury/metabolism; Apoptosis

Key words

Acute lung injury; Jinhua Qinggan granules; Neutrophil apoptosis; Nuclear factor kappa-B; Toll-like receptor 4

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Full text: 1 Database: MEDLINE Main subject: Influenza A Virus, H1N1 Subtype / Acute Lung Injury / COVID-19 Type of study: Prognostic_studies Limits: Animals Language: En Year: 2023 Type: Article

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