USP15 promotes cGAS activation through deubiquitylation and liquid condensation.

Shi, Chengrui; Yang, Xikang; Hou, Yanfei; Jin, Xue; Guo, Lerui; Zhou, Yi; Zhang, Conggang; Yin, Hang

Shi, Chengrui; Yang, Xikang; Hou, Yanfei; Jin, Xue; Guo, Lerui; Zhou, Yi; Zhang, Conggang; Yin, Hang.

Affiliation

Shi C; School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100082, China.
Yang X; Tsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Hou Y; Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing 100082, China.
Jin X; School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100082, China.
Guo L; Tsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Zhou Y; Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing 100082, China.
Zhang C; School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100082, China.
Yin H; Tsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China.

Nucleic Acids Res ; 50(19): 11093-11108, 2022 10 28.

Article in En | MEDLINE | ID: mdl-36243958

Subject(s)

Immunity, Innate; Nucleotidyltransferases; Nucleotidyltransferases/metabolism; Immunity, Innate/physiology; DNA/genetics; Signal Transduction/genetics

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