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Modeling and Assessing Osteoarthritis in Mice by Destabilization of the Medial Meniscus (DMM).
Miotla-Zarebska, Jadwiga; Parisi, Ida; Batchelor, Vicky; Vincent, Tonia L; Potter, Paul K.
Affiliation
  • Miotla-Zarebska J; Centre for Osteoarthritis Pathogenesis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
  • Parisi I; Centre for Osteoarthritis Pathogenesis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
  • Batchelor V; Centre for Osteoarthritis Pathogenesis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
  • Vincent TL; Centre for Osteoarthritis Pathogenesis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
  • Potter PK; Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK. ppotter@brookes.ac.uk.
Methods Mol Biol ; 2598: 357-373, 2023.
Article in En | MEDLINE | ID: mdl-36355305
ABSTRACT
In this chapter, we describe an induced model of osteoarthritis in mice, frequently employed in the study of this disease. We outline in detail the surgical induction of disease and preparation of samples for histological assessment of disease.
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Full text: 1 Database: MEDLINE Main subject: Osteoarthritis / Cartilage, Articular Limits: Animals Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Osteoarthritis / Cartilage, Articular Limits: Animals Language: En Year: 2023 Type: Article