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Combined germline pathogenic variants in FLCN and TP53 are associated with early onset renal cell carcinoma and brain tumors.
van de Beek, Irma; Glykofridis, Iris E; Wagner, Anja; den Toom, Dorine T; Bongers, Ernie M H F; van Leenders, Geert J L H; Johannesma, Paul C; Meijers-Heijboer, Hanne E J; Wolthuis, Rob M F; van Steensel, Maurice A M; Dubbink, Hendrikus J; Houweling, Arjan C.
Affiliation
  • van de Beek I; Department of Human Genetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Glykofridis IE; Department of Human Genetics, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Wagner A; Department of Clinical Genetics, University Medical Center Rotterdam, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • den Toom DT; Department of Pathology, University Medical Center Rotterdam, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Bongers EMHF; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van Leenders GJLH; Department of Pathology, University Medical Center Rotterdam, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Johannesma PC; Department of Pulmonology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Meijers-Heijboer HEJ; Department of Human Genetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Wolthuis RMF; Department of Human Genetics, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • van Steensel MAM; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
  • Dubbink HJ; Singapore Skin Research Institute, Agency for Science, Technology and Research, Singapore, Singapore.
  • Houweling AC; Department of Pathology, University Medical Center Rotterdam, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Mol Genet Genomic Med ; 11(2): e2098, 2023 02.
Article in En | MEDLINE | ID: mdl-36382415
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Full text: 1 Database: MEDLINE Main subject: Brain Neoplasms / Carcinoma, Renal Cell / Kidney Neoplasms Type of study: Risk_factors_studies Limits: Humans Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Brain Neoplasms / Carcinoma, Renal Cell / Kidney Neoplasms Type of study: Risk_factors_studies Limits: Humans Language: En Year: 2023 Type: Article