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Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats.
Muscat, Stephanie M; Deems, Nicholas P; Butler, Michael J; Scaria, Emmanuel A; Bettes, Menaz N; Cleary, Sean P; Bockbrader, Ross H; Maier, Steven F; Barrientos, Ruth M.
Affiliation
  • Muscat SM; Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio 43210.
  • Deems NP; Biomedical Sciences Graduate Program, The Ohio State University, Columbus, Ohio 43210.
  • Butler MJ; Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio 43210.
  • Scaria EA; Neuroscience Graduate Program, The Ohio State University, Columbus, Ohio 43210.
  • Bettes MN; Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio 43210.
  • Cleary SP; Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio 43210.
  • Bockbrader RH; Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio 43210.
  • Maier SF; Campus Chemical Instrumentation Center, The Ohio State University, Columbus, Ohio 43210.
  • Barrientos RM; Pharmaceutical Sciences Graduate Program, Division of Medicinal Chemistry and Pharmacognosy, The Ohio State University, Columbus, Ohio 43210.
J Neurosci ; 43(1): 155-172, 2023 01 04.
Article in En | MEDLINE | ID: mdl-36384680
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Full text: 1 Database: MEDLINE Main subject: Cognitive Dysfunction / Postoperative Cognitive Complications Type of study: Prognostic_studies Limits: Aged / Animals / Humans / Male Language: En Year: 2023 Type: Article
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Cognitive Dysfunction / Postoperative Cognitive Complications Type of study: Prognostic_studies Limits: Aged / Animals / Humans / Male Language: En Year: 2023 Type: Article