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High-Throughput Metabolic Soft-Spot Identification in Liver Microsomes by LC/UV/MS: Application of a Single Variable Incubation Time Approach.
Zhu, Yanlin; Chen, Guiying; Zhang, Kerong; Chen, Chang; Chen, Weiqing; Zhu, Mingshe; Jiang, Hongliang.
Affiliation
  • Zhu Y; DMPK Department Shanghai ChemPartner, Shanghai, 201203, China.
  • Chen G; Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430074, China.
  • Zhang K; AB Sciex, Beijing 100015, China.
  • Chen C; Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430074, China.
  • Chen W; DMPK Department Shanghai ChemPartner, Shanghai, 201203, China.
  • Zhu M; MassDefect Technologies, Princeton, NJ 08540, USA.
  • Jiang H; Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430074, China.
Molecules ; 27(22)2022 Nov 20.
Article in En | MEDLINE | ID: mdl-36432161
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Full text: 1 Database: MEDLINE Main subject: Microsomes, Liver / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Prognostic_studies / Qualitative_research Limits: Humans Language: En Year: 2022 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Microsomes, Liver / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Prognostic_studies / Qualitative_research Limits: Humans Language: En Year: 2022 Type: Article