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Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Jambeau, Melanie; Meyer, Kevin D; Hruska-Plochan, Marian; Tabet, Ricardos; Lee, Chao-Zong; Ray-Soni, Ananya; Aguilar, Corey; Savage, Kitty; Mishra, Nibha; Cavegn, Nicole; Borter, Petra; Lin, Chun-Chia; Jansen-West, Karen R; Jiang, Jie; Freyermuth, Fernande; Li, Nan; De Rossi, Pierre; Pérez-Berlanga, Manuela; Jiang, Xin; Daughrity, Lilian M; Pereira, João; Narayanan, Sarav; Gu, Yuanzheng; Dhokai, Shekhar; Dalkilic-Liddle, Isin; Maniecka, Zuzanna; Weber, Julien; Workman, Michael; McAlonis-Downes, Melissa; Berezovski, Eugene; Zhang, Yong-Jie; Berry, James; Wainger, Brian J; Kankel, Mark W; Rushe, Mia; Hock, Christoph; Nitsch, Roger M; Cleveland, Don W; Petrucelli, Leonard; Gendron, Tania F; Montrasio, Fabio; Grimm, Jan; Polymenidou, Magdalini; Lagier-Tourenne, Clotilde.
Affiliation
  • Jambeau M; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Meyer KD; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Hruska-Plochan M; Department of Quantitative Biomedicine, University of Zurich, Zurich CH-8057 Switzerland.
  • Tabet R; Neurimmune AG, Schlieren CH-8952 Switzerland.
  • Lee CZ; Institute for Regenerative Medicine, University of Zurich, CH-8952 Schlieren, Switzerland.
  • Ray-Soni A; Department of Quantitative Biomedicine, University of Zurich, Zurich CH-8057 Switzerland.
  • Aguilar C; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Savage K; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Mishra N; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Cavegn N; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Borter P; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Lin CC; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Jansen-West KR; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Jiang J; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Freyermuth F; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Li N; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • De Rossi P; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Pérez-Berlanga M; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Jiang X; Neurimmune AG, Schlieren CH-8952 Switzerland.
  • Daughrity LM; Neurimmune AG, Schlieren CH-8952 Switzerland.
  • Pereira J; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Narayanan S; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224.
  • Gu Y; Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, CA 92093.
  • Dhokai S; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Dalkilic-Liddle I; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Maniecka Z; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Weber J; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Workman M; Department of Quantitative Biomedicine, University of Zurich, Zurich CH-8057 Switzerland.
  • McAlonis-Downes M; Department of Quantitative Biomedicine, University of Zurich, Zurich CH-8057 Switzerland.
  • Berezovski E; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Zhang YJ; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Berry J; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224.
  • Wainger BJ; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Kankel MW; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Rushe M; Biogen, Cambridge, MA 02142.
  • Hock C; Biogen, Cambridge, MA 02142.
  • Nitsch RM; Biogen, Cambridge, MA 02142.
  • Cleveland DW; Biogen, Cambridge, MA 02142.
  • Petrucelli L; Department of Quantitative Biomedicine, University of Zurich, Zurich CH-8057 Switzerland.
  • Gendron TF; Department of Quantitative Biomedicine, University of Zurich, Zurich CH-8057 Switzerland.
  • Montrasio F; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Grimm J; Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, CA 92093.
  • Polymenidou M; Department of Neurology, The Sean M. Healey and AMG Center for ALS at the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.
  • Lagier-Tourenne C; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
Proc Natl Acad Sci U S A ; 119(49): e2123487119, 2022 12 06.
Article in En | MEDLINE | ID: mdl-36454749
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Full text: 1 Database: MEDLINE Main subject: Poly A / Genes, Regulator Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2022 Type: Article
Fulltext
Print
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PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Poly A / Genes, Regulator Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2022 Type: Article