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Inhibition of bone erosion, determined by high-resolution peripheral quantitative computed tomography (HR-pQCT), in rheumatoid arthritis patients receiving a conventional synthetic disease-modifying anti-rheumatic drug (csDMARD) plus denosumab vs csDMARD therapy alone: an open-label, randomized, parallel-group study.
Iwamoto, Naoki; Chiba, Ko; Sato, Shuntaro; Shiraishi, Kazuteru; Watanabe, Kounosuke; Oki, Nozomi; Okada, Akitomo; Koga, Tomohiro; Kawashiri, Shin-Ya; Tamai, Mami; Hosogaya, Naoki; Furuyama, Masako; Kobayashi, Makiko; Saito, Kengo; Okubo, Naoki; Uetani, Masataka; Osaki, Makoto; Kawakami, Atsushi.
Affiliation
  • Iwamoto N; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. naoki-iwa@nagasaki-u.ac.jp.
  • Chiba K; Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Sato S; Clinical Research Center, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Shiraishi K; Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Watanabe K; Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Oki N; Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Okada A; Department of Rheumatology, National Hospital Organization Nagasaki Medical Center, 2-1001-1 Kubara, Omura, Nagasaki, 856-8562, Japan.
  • Koga T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Kawashiri SY; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Tamai M; Departments of Community Medicine, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Hosogaya N; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Furuyama M; Clinical Research Center, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Kobayashi M; Department of Rheumatology, Nagasaki Kita Hospital, 800 Motomurago, Nishisonogigun Togitsucho, Nagasaki, 851-2103, Japan.
  • Saito K; Primary Medical Science Department, Medical Affairs Division, Daiichi Sankyo Co., Ltd, 3-5-1 Nihonbashi-Honcho, Chuo-ku, Tokyo, 103-8426, Japan.
  • Okubo N; Primary Medical Science Department, Medical Affairs Division, Daiichi Sankyo Co., Ltd, 3-5-1 Nihonbashi-Honcho, Chuo-ku, Tokyo, 103-8426, Japan.
  • Uetani M; Data Intelligence Department, Digital Transformation Management Division, Daiichi Sankyo Co., Ltd, 1-2-58, Hiromachi, Shinagawa-ku, Tokyo, 140-8710, Japan.
  • Osaki M; Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Kawakami A; Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Arthritis Res Ther ; 24(1): 264, 2022 12 07.
Article in En | MEDLINE | ID: mdl-36476479
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Full text: 1 Database: MEDLINE Main subject: Arthritis, Rheumatoid / Antirheumatic Agents Type of study: Clinical_trials Limits: Aged / Female / Humans / Male Country/Region as subject: Asia Language: En Year: 2022 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Arthritis, Rheumatoid / Antirheumatic Agents Type of study: Clinical_trials Limits: Aged / Female / Humans / Male Country/Region as subject: Asia Language: En Year: 2022 Type: Article