ERAP2 supports TCR recognition of three immunotherapy targeted tumor epitopes.

Schmidt, Karin; Leisegang, Matthias; Kloetzel, Peter-Michael

Schmidt, Karin; Leisegang, Matthias; Kloetzel, Peter-Michael.

Affiliation

Schmidt K; Institute für Biochemie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Biochemistry, Berlin, Germany. Electronic address: Ka.Sdt@gmx.de.
Leisegang M; Institute of Immunology Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany; David and Etta Jonas Center for Cellular Therapy, The University of Chicago, Chicago, USA; German Cancer Consortium (DKTK), partner site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kloetzel PM; Institute für Biochemie Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Biochemistry, Berlin, Germany. Electronic address: p-m.kloetzel@charite.de.

Mol Immunol ; 154: 61-68, 2023 02.

Article in En | MEDLINE | ID: mdl-36608422

Subject(s)

Monophenol Monooxygenase; Neoplasms; Humans; Peptides/metabolism; Epitopes, T-Lymphocyte; Receptors, Antigen, T-Cell; Immunotherapy; Aminopeptidases; Minor Histocompatibility Antigens/metabolism

Key words

Adoptive T-cell therapy; Antigen presentation; Antigen processing; ER-resident aminopeptidases; MHC class I

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Full text: 1 Database: MEDLINE Main subject: Monophenol Monooxygenase / Neoplasms Limits: Humans Language: En Year: 2023 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Monophenol Monooxygenase / Neoplasms Limits: Humans Language: En Year: 2023 Type: Article