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Unlocking geminal fluorohaloalkanes in nucleophilic fluoroalkylation chemistry: generation and trapping of lithiumfluorocarbenoids enabled by flow microreactors.
Spennacchio, Mauro; Colella, Marco; Andresini, Michael; Dibenedetto, Roberta Savina; Graziano, Elena; Aramini, Andrea; Degennaro, Leonardo; Luisi, Renzo.
Affiliation
  • Spennacchio M; Flow Chemistry and Microreactor Technology FLAME-Lab, Department of Pharmacy - Drug Sciences, University of Bari "A. Moro", Bari, 70125, Italy. renzo.luisi@uniba.it.
  • Colella M; Flow Chemistry and Microreactor Technology FLAME-Lab, Department of Pharmacy - Drug Sciences, University of Bari "A. Moro", Bari, 70125, Italy. renzo.luisi@uniba.it.
  • Andresini M; Flow Chemistry and Microreactor Technology FLAME-Lab, Department of Pharmacy - Drug Sciences, University of Bari "A. Moro", Bari, 70125, Italy. renzo.luisi@uniba.it.
  • Dibenedetto RS; Flow Chemistry and Microreactor Technology FLAME-Lab, Department of Pharmacy - Drug Sciences, University of Bari "A. Moro", Bari, 70125, Italy. renzo.luisi@uniba.it.
  • Graziano E; Flow Chemistry and Microreactor Technology FLAME-Lab, Department of Pharmacy - Drug Sciences, University of Bari "A. Moro", Bari, 70125, Italy. renzo.luisi@uniba.it.
  • Aramini A; Department of Discovery, Dompé Farmaceutici S.p.A., Via Campo di Pile, L'Aquila, 67100, Italy.
  • Degennaro L; Flow Chemistry and Microreactor Technology FLAME-Lab, Department of Pharmacy - Drug Sciences, University of Bari "A. Moro", Bari, 70125, Italy. renzo.luisi@uniba.it.
  • Luisi R; Flow Chemistry and Microreactor Technology FLAME-Lab, Department of Pharmacy - Drug Sciences, University of Bari "A. Moro", Bari, 70125, Italy. renzo.luisi@uniba.it.
Chem Commun (Camb) ; 59(10): 1373-1376, 2023 Jan 31.
Article in En | MEDLINE | ID: mdl-36649092
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Full text: 1 Database: MEDLINE Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Language: En Year: 2023 Type: Article