Enhanced production of surfactin using cassava wastewater and hydrophobic inducers: a prospection on new homologues.
World J Microbiol Biotechnol
; 39(3): 82, 2023 Jan 20.
Article
in En
| MEDLINE
| ID: mdl-36658370
ABSTRACT
Biosurfactants are amphipathic molecules that can be applied in a wide range of areas. The cost of production limits the industrial application of biosurfactants. Nevertheless, the biosurfactant productivity can be easily enhanced by inducers. This work aimed to investigate the effect of hydrophobic inducers on surfactin production by B. subtilis ATCC 6633 using cassava wastewater as low-cost culture medium. The submerged cultivation was carried out at 30 °C, 150 rpm for 72 h. The fermentation parameters used were bacterial growth, consumption of sugars, and surfactin production, including surfactin homologues. The surface tension decreased by 40% after 12 h, when compared to control. Depletion of sugars was observed in all experiments. Palmitic acid led to the highest yield in terms of surfactin production (≈ 1.3 g·L- 1 of pure surfactin). The inducers triggered the production of new surfactin homologues, that represent, potentially, new biological activities.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Bacillus subtilis
/
Manihot
Language:
En
Year:
2023
Type:
Article