The role of conformational change and key glutamic acid residues in the ClC-ec1 antiporter.

Yue, Zhi; Li, Chenghan; Voth, Gregory A.

Affiliation

Yue Z; Department of Chemistry, Chicago Center for Theoretical Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois.
Li C; Department of Chemistry, Chicago Center for Theoretical Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois.
Voth GA; Department of Chemistry, Chicago Center for Theoretical Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois. Electronic address: gavoth@uchicago.edu.

Biophys J ; 122(6): 1068-1085, 2023 03 21.

Article in En | MEDLINE | ID: mdl-36698313

Subject(s)

Antiporters; Escherichia coli Proteins; Antiporters/genetics; Antiporters/metabolism; Glutamic Acid/chemistry; Glutamine; Chlorides/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Protons; Chloride Channels/metabolism; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism