Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts.

Liscum, L; Faust, J R

Liscum, L; Faust, J R.

Affiliation

Liscum L; Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts 02111.

J Biol Chem ; 262(35): 17002-8, 1987 Dec 15.

Article in En | MEDLINE | ID: mdl-3680287

Subject(s)

Cholesterol/biosynthesis; Lipoproteins, LDL/metabolism; Niemann-Pick Diseases/metabolism; Cholesterol Esters/metabolism; Fibroblasts/metabolism; Humans; Hydroxycholesterols/metabolism; Time Factors

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PubMed Links

Database: MEDLINE Main subject: Niemann-Pick Diseases / Cholesterol / Lipoproteins, LDL Limits: Humans Language: En Year: 1987 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Niemann-Pick Diseases / Cholesterol / Lipoproteins, LDL Limits: Humans Language: En Year: 1987 Type: Article